Advancing our understanding of brain function and dysfunction through innovative research at Trinity College Dublin
The lab for Clinical and Integrative Neuroscience (lab CLINT) is part of the Trinity College Institute for Neuroscience at Trinity College Dublin. Our mission is to deepen understanding of human brain function and translate this knowledge into better treatments for psychiatric and neurological disorders.
We combine advanced multimodal brain imaging with innovative invasive and non-invasive neuromodulation approaches to uncover the mechanisms of neuroplasticity dysfunction. In particular, we study how adaptive and maladaptive plasticity shape brain health and disease, with the goal of developing new therapies for neurological conditions such as chronic pain, tinnitus, Parkinson’s disease, and cognitive impairment, as well as psychiatric disorders including addiction, OCD, and depression.
Studying specific neurological and psychiatric disorders to develop biomarkers and novel therapeutic approaches.
Understanding the brain’s capacity for change — its neural plasticity — in both adaptive and maladaptive contexts.
Developing personalized neuromodulation treatment strategies for specific specific neurological and psychiatric conditions.
Published in The Lancet, 2026
A global analysis reveals that mental disorders are rising worldwide, placing a growing and unequal burden on health systems and communities.
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Published in Nature Reviews Disease Primers, 2026
This study reframes tinnitus as more than “ringing in the ears”: a common, complex brain–ear disorder shaped by hearing injury, neural plasticity, stress and comorbidities, while pointing toward more personalized diagnosis and emerging treatments.
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The Textbook of Tinnitus (2nd edition), with contributions from the lab CLINT team, provides a comprehensive overview of the mechanisms, diagnosis, and treatments, reflecting major advances in tinnitus research.
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BRAI3N clinic is implementing novel treatments developed at lab CLINT by translating our scientific findings into personalized, innovative therapies to treat specific neurological and psychiatric conditions.
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The goal of consortium is to develop an objective, AI-based biomarker for diagnosing tinnitus, advancing patient care and enabling investment from the pharmaceutical and hearing technology industries.
Read MoreWe welcome collaborations, student inquiries, and research partnerships. Reach out to learn more about our work.
Trinity College Institute of Neuroscience - Lloyd Building
The University of Dublin - Trinity College Dublin
College Green
Dublin
Ireland
lab.CLINT@tcd.ie