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Ebook: Towards an Understanding of Tinnitus Heterogeneity


Frontiers e-book comprised all the articles featured in the Research Topic: Towards an Understanding of Tinnitus Heterogeneity that was edited by Christopher Cederroth, Arnaud Norena, Berthold Langguth, Winfried Schlee, Sven Vanneste, Tobias Kleinjung, Jose Antonio Lopez-Escamez, Pim Van Dijk, Martin Meyer, Grant Searchfield, Peyman Adjamian, Rilana Cima, Deborah A Hall, Birgit Mazurek, Heidi Olze, Giriraj Singh Shekhawat, Nathan Weisz, Silvano Gallus, Jianxin Bao, Antonello Maruotti, Rüdiger Christoph Pryss, Manfred Reichert, Thomas Probst, Bård Støve and Myra Spiliopoulou.

This Frontiers research topic aims to provide an inter- and multi-disciplinary survey of cutting-edge research in tinnitus, in order to better understand tinnitus heterogeneity and improve therapeutic outcomes. This requires the coordinated effort of multiple scientific disciplines including neuroscience, neurology, genetics, audiology, otolaryngology, psychology, psychiatry, pharmacology, epidemiology, medical informatics, data mining and statistics.The special issue includes 80 articles by 333 experts in tinnitus.



New research paper


In a new paper we investigate whether a correlation exists between tinnitus behavioural scores and functional brain connectivity of five resting-state networks comprising the auditory, the default mode, the external control left and right, and the salience network. Our results indicate that alterations of functional interactions between key neural circuits of the brain are not limited to one single network. In particular, tinnitus distress shows a strong correlation with the connectivity pattern within and between the right executive control network and the other four resting-state networks, indicating that tinnitus distress is probably the consequence of a hyperactive attention condition. Among the behavioural scores, the strongest correlation is observed between age and hearing loss, while the tinnitus objective loudness was not correlated with any behavioural scores.


World Expert


Professor Vanneste has been recognized as a ‘World Expert’ in Tinnitus (top 3) and Hearing Disorders (top 5) by the US-based medical website Expertscape which placed him in the top 0.1% of experts in his field.

Expertscape ranks researchers and clinicians according to the quantity and quality of their publications in the medical literature between 2008 and 2019.


New Publication


A new paper published in Neuroscience & Biobehavioral Reviews by lab members Dr. Hullfish and Dr. Vanneste conclude that predictive coding offers the basis for a unifying theory of cognitive neuroscience, which we demonstrate with several examples linking tinnitus to other lines of brain research.


Lab for Clinical & Integrative Neuroscience, Institute for Neuroscience & Global Brain Health Institute, Trinity College Dublin © 2019